From vibrant cities and legendary beaches to dramatic mountains, remote islands and some of the most extraordinary wildlife on Earth, South America is made for an unforgettable cruise adventure.
A South America cruise gives you the chance to experience several incredible destinations in one journey, from Brazil, Chile and Argentina to Uruguay and Peru. Looking for an even bigger adventure? Choose an itinerary that ventures to the Falkland Islands, Cape Horn or Antarctica, where you may spot penguins, sea lions, elephant seals and other remarkable wildlife. 
From the southern tip of South America to the icy landscapes of Antarctica, this is a cruise you'll remember for a lifetime. Read More
The eastern coast of South America is home to some of the continent's most exciting cities and destinations. Start in Buenos Aires, Argentina, a vibrant city known for its European-inspired architecture, lively neighborhoods, incredible food and passionate tango culture.
Wander through colorful streets, browse local markets and enjoy an authentic Argentine meal before experiencing the city's famous tango scene.
Further north, Rio de Janeiro delivers a completely different experience. Famous for its legendary Carnival, spectacular beaches and iconic landmarks, Rio is one of the most exciting stops on a South America cruise.
Take in the views from Sugarloaf Mountain, relax on Copacabana Beach or explore Tijuca National Park, one of the world's largest urban forests. Depending on your itinerary, you may also visit Ilha Grande off the Brazilian coast or Punta del Este in Uruguay for even more variety.

The western coast of South America offers a spectacular combination of cities, culture and dramatic scenery. In Chile, many cruise itineraries call at San Antonio, giving you the opportunity to explore the port or travel inland to Santiago, the country's capital. With the Andes Mountains forming a spectacular backdrop, Santiago is a fantastic place to experience Chilean culture, cuisine and city life. Ride the cable car for panoramic views over the city and the Andes, explore local markets and museums, or enjoy a meal at one of the city's acclaimed restaurants. 
Some South America cruise itineraries continue north to Lima, Peru. Located along the Pacific coast, Lima combines fascinating history, vibrant culture and some of the best cuisine in South America. For an even more unforgettable adventure, look for itineraries that include the Galápagos Islands. Surrounded by crystal-clear waters, this remarkable archipelago is famous for its unique wildlife and extraordinary landscapes. Spot giant tortoises
, sea lions, penguins and marine iguanas as you explore one of the world's most fascinating wildlife destinations.
Princess Cruises, Oceania Cruises and MSC Cruises offer a variety of South America cruises, from shorter coastal itineraries to longer journeys that combine multiple countries and regions. Whether you're dreaming of Brazil and Argentina, exploring Chile and Peru, sailing around Cape Horn or venturing toward Antarctica, there's a South America cruise for every kind of traveler. Explore our itineraries and start planning your next adventure.